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  "Culovort isn't a cancer drug, but it's used in conjunction with other chemo drugs for a wide range of cancers," he'd explained to her. "The kicker is that Culovort is critical in treating colon cancer. It's used along with another cancer drug, Fluorouracil, or 5-FU, as it's commonly called. Think of 5-FU as a grenade that masquerades as a component of DNA and explodes inside the cancer cells. Culovort is an accomplice that helps it get past the guards. Without the Culovort, you've got all the toxic poison of 5-FU, but fewer cancer cells getting killed."

  He steepled his long thin fingers together, and looked over them as he spoke. "The problem is, Culovort is off patent and therefore it's cheap."

  Erin said, "That's a problem? Oh, I see."

  Edward Kender nodded. "Schiffer Hartwin Pharmaceutical makes only a negligible profit off it. Without it, the people suffering from colon cancer are the biggest losers, like my father. With no Culovort, they'll be forced to use the new oral drug-Eloxium. Some believe the oral drug is better-but the thing is, Eloxium can cost twenty thousand dollars for the treatment course.

  "Most insurance companies do not cover the oral treatment, or only a small part of it, which means that many colon cancer patients will have to come up with thousands of dollars to pay for the Eloxium. Dad's oncologist is furious about it because she'll have to force patients over to the oral medication. There'll be simply no choice once there's no supply. Even worse, if a patient begins the Eloxium, there's no going back, even if Culovort becomes available again."

  Erin said slowly, "So mortgage your home to pay for the treatment of a life-threatening disease, and have a nice day."

  "Can you imagine, Erin, not only dealing with chemotherapy and all the brutal side effects, the possible prospect of dying, your family's grinding fear, the unending stress, and then being told that one of the major components of your chemotherapy course isn't available anymore because of unexpected production problems? And, oh, yes, sorry, but on top of all that, it's going to cost you a bundle out-of-pocket to switch over to a new chemo drug."

  Oh, yes, she could imagine it. She remembered all too well her father's final months, the soul-draining helplessness they'd all felt watching her father become a frail old man, so ill he couldn't eat, so weak he could barely stand. She remembered how he'd told her late one night that this damnable cure made you forget the disease, you felt so rotten. She swallowed down tears, shook her head. "What I really can't picture is a group of people actually sitting down and deciding to simply stop making an important medicine for cancer patients, people who may already be staring at death from the doorway and trying to deal with it."

  Dr. Kender smiled at her, a charming smile that for an instant erased the terrible fatigue and worry from his eyes. "Ah, you're forgetting the bankers on Wall Street. They purposely set out to make all the money they could, and they didn't seem to give a damn about the consequences."

  Erin sighed. "I'm beginning to wonder if greed has any limits at all."

  He said, "We are the ones who have to set those limits. Controlling and manipulating access to drugs for profit is wrong, but at least it affects a finite number of people. The bankers have damaged the entire world."

  He drummed his fingertips on the arm of his chair. "At any rate, Erin, I went to see Mr. Caskie Royal, the CEO of the U.S. subsidiary of Schiffer Hartwin Pharmaceutical, located right down the road in Stone Bridge. He agreed to see me because he fancied I was some sort of big-wig professor from Yale."

  "You are."

  He tried to laugh, but only dredged up a small smile. "Disease is the great leveler, Erin. If you're facing death, nothing else exists-money, fame, power all cease to be important. As for Caskie Royal, he said he was sympathetic, then actually threw his hands in the air. Told me he was trying his best to solve the unexpected production line problems brought on by overenthusiastic expansion, was the way he put it." Dr. Kender lowered his eyes to his clasped hands. "As if any moron would believe that. I mean, a company wants to expand and it doesn't determine the effects of said expansion on its current production of drugs?

  "It's a lie, of course. I'll admit it, I wanted to pull him out of his big executive chair and choke the life out of him.

  "There is another Schiffer Hartwin production laboratory for Culovort in Spain. Their PR folk came up with a new reason for aborting production-quality-control issues, they said, and even the possibility the production line might have been sabotaged. It will take them some time to ramp up production again, blah, blah, blah."

  "What about the media?"

  "The fact that a cancer drug isn't available isn't sexy enough for the national media to make a big issue of it, since there's a different drug on the market. The Wall Street Journal and The Washington Post reported on the shortage and Schiffer Hartwin's response, but that's it. No digging, no real questioning of the company, and those two newspapers usually take an interest in medicine."

  Dr. Kender looked like he was at the end of his rope. There was anger in his gaunt face, but more than that, there was a sheen of hopelessness. He said on a sigh, "My dad, you never met him, Erin. He's old school, tough as nails, determined to take care of himself. We've discussed going on the oral cancer drug, but he's heard too many horror stories about the side effects, and he can't afford it in any case. If he's forced to go on it, he'll probably sell his house, and he's already told me there's no way he'll let me help. I've wanted to choke him for his misplaced pride, even though I completely understand it."

  He paused a moment. "I hate that he's suffering, and now this worrying about having to come up with twenty thousand dollars when the Culovort runs out. It's breaking his will. I don't want him to die like this." He looked down at his tasseled loafers, his shoulders bowed, like a man who's gone up against the giant and gotten smashed. Erin wanted to weep.

  He said quietly, "Do you know that in the U.S., about one hundred and fifty thousand people are diagnosed with colon cancer every year? I've written letters, sent e-mails, made phone calls to my elected representatives, to the FDA, until all I wanted was to shoot myself. No one seems to care except for the oncologists, the patients, and their beleaguered families, and they're powerless. I don't really know why I'm here. I knew you'd understand, Erin, but what can you do? What can anyone do to force the drug company to start up Culovort to full production again?"

  "What we need," Erin said, drumming her fingertips on the little banged-up desk she'd bought from Goodwill in her sophomore year at Boston College, "is to get hold of solid proof they know damned well what they're doing, and that they are profiting from it. Then the media will sit up and pay attention. They love drug company scandals, but they like them much more when they're presented on a nice big platter complete with fines of hundreds of million dollars."

  She rose, took both his hands in hers. "I don't know yet what I'm going to do, sir, but I do know that I'm going to try my best to find something that will help. Let me think about this, all right?"

  She knew he'd left without much hope, but she was fired up, her brain cooking. She spent three hours that evening on the Internet searching out everything on the Culovort shortage, but found little more than Dr. Kender had already told her. Everywhere the same thing, in other words, the company line: Production line problems, overexpansion, it was being worked on, but it would take time. It was when she read about how the oncology departments at major university medical schools were beginning to ration Culovort that she kicked her desk.

  Why didn't someone in power question what the drug company said? Didn't any of these vaunted medical reporters remember the drug companies' record of gross misconduct-hiding negative data from the FDA, practically bribing physicians, failing to publish negative results, ghostwriting journal articles-and start waving red flags immediately, when it might make a difference? Didn't they remember the Vioxx scandal? How many people had died before Merck was forced to pull that drug?

  Was this simply the way all drug companies operated worldwide? Come to think of it, was th
is the way politicians operated? Was self-interest the only driving force?

  She was depressing herself.

  What she needed was rock-solid proof that Schiffer Hartwin was doing this knowingly, and for profit. By midnight, she'd decided her old lock picks were her best shot at getting proof and forcing the Culovort production line to get up-and-running again.

  3

  STONE BRIDGE, CONNECTICUT

  Monday morning

  As Erin chewed on her English muffin, she reread the nineteen pages she'd photocopied from the Project A file. There was plenty there, even explanations the PR people were to give for the breakdown in Culovort production they knew would impact cancer patients. Caskie Royal had been wonderfully thorough in his To Do list, including one bulleted sentence that summed it all up: Given current worldwide Culovort supplies and current production levels at our facility in Spain, we estimate it will require four months for Culovort shortages to develop in the U.S. Shortages will force many oncologists to switch to Eloxium.

  And then they shut down production in Spain!

  Erin frowned. She realized all of this would make much more sense if Schiffer Hartwin also owned the patent for the enormously expensive oral drug Eloxium.

  But they didn't. A French pharmaceutical company, Laboratoires Ancondor, produced Eloxium. Dr. Kender had told her one hundred and fifty thousand people in the U.S. were diagnosed with colon cancer each year. The income from Eloxium would end in more zeros than she could count.

  But why would a German pharmaceutical cut way back on its Culovort production in its U.S. and Spanish facilities so a French pharmaceutical company could reap the profits?

  Clearly, antitrust laws wouldn't allow them to profit directly. Was there some other way they were scratching each other's backs? Were there payoffs involved? Swiss bank accounts? Or were they so arrogant as to believe there would be no legal action if they violated the antitrust laws?

  Erin smeared more crunchy peanut butter on her English muffin as she read about Serono, a Swiss biopharmaceutical company, that had tried to bring an AIDS drug to market "by concocting a dubious medical test," U.S. Attorney General Alberto R. Gonzales had alleged. The company "put its desire to sell the drug above the interests of patients." Serono had even offered doctors an all-expenses-paid trip to France to prescribe the drug.

  Did she have to add doctors to the growing list of endlessly greedy professions?

  She laid aside the stack of printouts that documented incredibly creative bad deeds by the pharmaceutical companies. What she needed now was to act. She began to refine her list of media people to contact with the papers she'd copied off Royal's files. It was going to be tricky since she didn't want to go to jail for breaking into Caskie Royal's computer. She finally selected Paul Bradley at The Wall Street Journal and Luther Gleason of The New York Times, as both had reported on the Culovort shortage. None of the major TV stations had reported on the Culovort shortage and its consequences to colon cancer patients. When this story broke in the newspapers, though, Katie Couric, in particular, would be all over it.

  Her head snapped up when she heard a TV reporter say, "The body of a man was discovered two hours ago in Van Wie Park-"

  Van Wie Park was right behind Schiffer Hartwin's American headquarters. She grabbed her cup of tea and sat down in front of the TV. A reporter shoved his microphone into a man's face. "This is Special Agent in Charge of the New Haven field office, Bowie Richards. Special Agent, what do you know about this death? Was it murder? Why is this in the hands of the FBI and not the Stone Bridge police department? Have you identified the victim? Do you believe it connects to the break-in at the U.S. subsidiary headquarters of Schiffer Hartwin last night?"

  Agent Bowie Richards looked both pained and grateful at the reporter's shotgun approach, Erin thought, since it allowed him to pick and choose. "The FBI was called in because the victim was found in Van Wie Park, which is federal land. The FBI and the local police department will be working together to solve this brutal crime. That's all I have to say at the moment." He turned and nodded to a portly middle-aged man the reporter introduced as Police Chief Clifford Amos, who didn't seem at all happy that the victim had the bad judgment to get whacked on federal land.

  "Chief, have you identified the victim?"

  Police Chief Amos said, "The FBI wishes to withhold his identity until the family is contacted. As Special Agent Richards said, my department will be closely involved in this case."

  Yeah, sure you will, Erin thought. If she were Bowie Richards, she'd keep the local cops as far out of the loop as possible. A dead guy murdered in Caskie Royal's backyard and I was there, or maybe close by, when it happened. I could have stumbled over the body, maybe run headlong into the murderer. They'll find out I was in Caskie Royal's office, lifting documents from his computer, and they'll think I murdered him. I'll go to jail and Dr. Kender's father will have to sell his house to pay for the Eloxium and- Slow down, slow down. Was the murdered man an employee of Schiffer Hartwin? The way the world worked, she'd bet the last bite of her English muffin on it, with an extra spoonful of peanut butter smeared on top.

  Could it be possible the dead guy had nothing to do with Schiffer Hartwin? Maybe he was just an unlucky out-of-towner, here to visit his mother, who managed to get mugged and killed? That was too good to believe. And if he was connected to Schiffer Hartwin, did his death have anything to do with her being there?

  Fact was, she hadn't seen a thing, hadn't heard a thing, hadn't stumbled over a dead body, not, of course, that a single soul would believe her.

  Then it hit her hard. How could she give all the documents from Caskie Royal's computer to the media now? She'd have her butt arrested within an hour.

  Whatever she did, from this moment on, she was going to have to be very careful she wouldn't be connected to the murder.

  When the doorbell rang an hour later, Erin was just beginning to organize her notes, Royal's Project A file, and her printouts and clippings.

  As was her habit, she looked through the peephole instead of flinging open her door to avoid welcoming in a vampire or other miscreant. Good grief, hadn't she just seen that face on TV? She felt her heart fall to her toes. They'd found out about her so soon? No, impossible. She had to get a grip. "Who is it?"

  "My name's Bowie Richards. May I speak to you, Ms. Pulaski?"

  "Why?" But she knew why. They'd found a witness who'd gotten the license plate number off her Hummer, or the guard had somehow seen her on a camera she hadn't known was there and she'd been identified by Carla Alvarez, who'd recognized her from the gym or-

  "It's personal, Ms. Pulaski. It's about my daughter, Georgie."

  What? Georgia Richards-Georgie-was the daughter of an FBI agent? No, more than that-Bowie Richards was the big-cheese FBI agent in New Haven. Why hadn't anyone said anything? She felt a huge black cloud moving swiftly toward her and she wondered in that moment if her family's legendary good luck was fast heading south.

  She didn't want to, but she opened the door and stepped up to block the doorway.

  Bowie Richards looked different in person-bigger, and harder, and to her panicked eyes, the Agent of Doom embodied in a dark suit, white shirt, red and blue tie, and black wingtips. He was young to have the position of Special Agent in Charge in an FBI field office, no more than early thirties. He was olive-complexioned, his hair dark brown, his eyes light blue, with a lean, rangy runner's body.

  She didn't move from the open doorway. "You're Georgie's father?"

  He stuck out his hand and she automatically shook it. A really strong hand that could twist her small .22 around her fingers, and laugh. "Bowie Richards. Ah, do you have a few minutes, Ms. Pulaski? It seems I'm badly in need of your help."

  She couldn't let him in, he'd see all the Culovort pages, all the stuff she'd copied off the Internet about drug company scandals. All her work sheets were still spread out haphazardly on the dining room table. It wouldn't take him more than two seconds to realize he'
d walked right in on a potential murder suspect. Five minutes later and all those damning pages would have been in folders and tucked away. Her good luck was indeed now traveling south at warp speed.

  Erin said, "Sorry, but I can't let you in. I just sprayed for bugs and the smell's toxic. I'm sure you can smell it from here so don't breathe deeply. I just took off my mask. Let me step out into the hallway." She closed the door behind her.

  Erin smiled at him brightly. "What about Georgie?"

  Bowie wondered what was going on here. He hadn't smelled a thing. If she'd worn a mask, where were the marks on her face? Why didn't she want to let him in? Ah, there was probably a guy in there, and she didn't want him to be seen. But why? Maybe because the guy was married?

  He leaned against the hallway wall, crossed his arms over his chest. The pose was intimidating, only he didn't realize it. Erin stood in front of him, her hands stuck in her jeans pockets, wondering what demon convinced her to work at home this morning, and prayed.

  "My daughter is always talking about you, Ms. Pulaski. She told me you walked in the first day of class and announced to all the children and their parents that your name was Erin Pulaski and you were a Polish-Irish-American. I laughed at that, and so Georgie kept repeating it, at least half a dozen more times. I believe she's repeated every word out of your mouth. I suppose I feel like I know you and so that's why I came to you. I know I can trust you."